Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep330 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Use of statins and cognitive performance in elderly type 2 diabetic patients

Fagotto Valentina , Colussi GianLuca , Da Porto Andrea , Cavarape Alessandro , Alberto Sechi Leonardo

Background: Type 2 diabetes (T2D) is known as risk factor for mild cognitive impairment (MCI), which can lead to confirmed dementia. T2D patients often take statins for cardiovascular prevention but, nowadays, it is not clear if these drugs could also prevent cognitive impairment.Objective: We aimed to evaluate the association between statins in primary or secondary cardiovascular prevention and cognitive performance in old T2D patients referring to our ...

ea0070aep339 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Correlation between BMI and cognitive performance in type 2 diabetic patients

Fagotto Valentina , Colussi GianLuca , Da Porto Andrea , Cavarape Alessandro , Alberto Sechi Leonardo

Background: The association between diabetes (DM) and cognitive impairment is already well established. DM affects multiple superior domains, in primis working memory and executive functions and damages nervous system in both morphological and functional ways. The Montreal Cognitive Assessment(MoCA) is a neuropsychological test defined as the best tool evaluating mild cognitive impairment (MCI) in DM.Objective: Our study aimed to invest...

ea0063p34 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Aldosterone measurement in the Diagnosis of primary aldosteronism – comparison between two automated immunoassays and two liquid chromatography tandem mass-spectrometry methods

Fagotto Valentina , Uhl Olaf , Heinrich Daniel , Nirschl Nina , Sturm Lisa , Kratzsch Jurgen , Bae Yoon Ju , Fries Charlotte , Fenske Wiebke , Reincke Martin , Bidlingmaier Martin

Poor agreement between different analytical methods measuring aldosterone concentrations impedes applicability of uniform cut-offs in the diagnostic work-up of primary aldosteronism (PA). We compared 4 analytical methods (2 immunoassays and 2 LC-MS/MS) in plasma samples before and after saline infusion test (SIT). 80 hypertensive patients underwent the standardized diagnostic work-up within the German Conn’s registry. Patients (PA n=39/non-PA n=41) were ...